Carboxyl Silver Nanoparticles
Carboxyl functionalized silver nanoparticles are ideal for conjugation of proteins and other primary amine containing ligands using standard EDC/NHS coupling chemistry.
Our carboxylated silver nanoparticles are available in 8 different sizes ranging from 10-100nm, are more than 95% spherical and have uniform size distribution (CV <18%). In addition, the choice of two different length PEG surface spacer allows control of the distance between a conjugated molecule and the silver surface.
Features
- Superior size distribution compared to the leading competitor; available from 10nm to 100nm.
- Precisely engineered surface with an optimized carboxyl group density for easy conjugation.
Applications
- Ideal for development of silver conjugates for use in for example:
- Immunoblotting
- Lateral Flow Assays
- LSPR Assays
- Microscopy Applications (e.g. TEM, Darkfield)
100nm Carboxylated (carboxyl-PEG5000-SH) Silver Nanoparticles
RN-CY-SC5K-100-25
Silver nanoparticle core size: 10,20,30,40,50,60,80,100nm (+/- 3nm)
Size dispersity: CV <15%
Surface composition: carboxyl-PEG5000-SH/methoxy-PEG2000-SH
Carboxyl surface density: 1/nm2
Concentration: 1mg/ml
Formulation: Supplied in USP grade purified water
100nm Carboxylated (carboxyl-PEG3000-SH) Silver Nanoparticles
RN-CY-SC3K-100-25
Silver nanoparticle core size: 100nm (+/- 3nm)
Size dispersity: CV <15%
Surface composition: carboxyl-PEG3000-SH/methoxy-PEG2000-SH
Carboxyl surface density: 1/nm2
Absorption max: 480-520nm
Concentration: 1mg/ml
Optical Density (OD): 46
Particles per ml: ~1.8E+11
Formulation: Supplied in USP grade purified water
80nm Carboxylated (carboxyl-PEG5000-SH) Silver Nanoparticles
RN-CY-SC5K-80-25
Silver nanoparticle core size: 80nm (+/- 3nm)
Size dispersity: CV <15%
Surface composition: carboxyl-PEG5000-SH/methoxy-PEG2000-SH
Carboxyl surface density: 1/nm2
Absorption max: 445-465nm
Concentration: 1mg/ml
Optical Density (OD): 80
Particles per ml: ~3.5E+11
Formulation: Supplied in USP grade purified water
80nm Carboxylated (carboxyl-PEG3000-SH) Silver Nanoparticles
RN-CY-SC3K-80-25
Silver nanoparticle core size: 80nm (+/- 3nm)
Size dispersity: CV <15%
Surface composition: carboxyl-PEG3000-SH/methoxy-PEG2000-SH
Carboxyl surface density: 1/nm2
Absorption max: 445-465nm
Concentration: 1mg/ml
Optical Density (OD): 80
Particles per ml: ~3.5E+11
Formulation: Supplied in USP grade purified water
60nm Carboxylated (carboxyl-PEG5000-SH) Silver Nanoparticles
RN-CY-SC5K-60-25
Silver nanoparticle core size: 60nm (+/- 3nm)
Size dispersity: CV <15%
Surface composition: carboxyl-PEG5000-SH/methoxy-PEG2000-SH
Carboxyl surface density: 1/nm2
Absorption max: 425-440nm
Concentration: 1mg/ml
Optical Density (OD): 100
Particles per ml: ~8.5E+11
Formulation: Supplied in USP grade purified water
60nm Carboxylated (carboxyl-PEG3000-SH) Silver Nanoparticles
RN-CY-SC3K-60-25
Silver nanoparticle core size: 60nm (+/- 3nm)
Size dispersity: CV <15%
Surface composition: carboxyl-PEG3000-SH/methoxy-PEG2000-SH
Carboxyl surface density: 1/nm2
Absorption max: 425-440nm
Concentration: 1mg/ml
Optical Density (OD): 100
Particles per ml: ~8.5E+11
Formulation: Supplied in USP grade purified water
50nm Carboxylated (carboxyl-PEG5000-SH) Silver Nanoparticles
RN-CY-SC5K-50-25
Silver nanoparticle core size: 50nm (+/- 3nm)
Size dispersity: CV <18%
Surface composition: carboxyl-PEG5000-SH/methoxy-PEG2000-SH
Carboxyl surface density: 1/nm2
Absorption max: 415-430nm
Concentration: 1mg/ml
Optical Density (OD): 125
Particles per ml: ~1.4E+12
Formulation: Supplied in USP grade purified water
50nm Carboxylated (carboxyl-PEG3000-SH) Silver Nanoparticles
RN-CY-SC3K-50-25
Silver nanoparticle core size: 50nm (+/- 3nm)
Size dispersity: CV <18%
Surface composition: carboxyl-PEG3000-SH/methoxy-PEG2000-SH
Carboxyl surface density: 1/nm2
Absorption max: 415-430nm
Concentration: 1mg/ml
Optical Density (OD): 125
Particles per ml: ~1.4E+12
Formulation: Supplied in USP grade purified water
40nm Carboxylated (carboxyl-PEG5000-SH) Silver Nanoparticles
RN-CY-SC5K-40-25
Silver nanoparticle core size: 40nm (+/- 3nm)
Size dispersity: CV <18%
Surface composition: carboxyl-PEG5000-SH/methoxy-PEG2000-SH
Carboxyl surface density: 1/nm2
Absorption max: 410-425nm
Concentration: 1mg/ml
Optical Density (OD): 125
Particles per ml: ~2.8E+12
Formulation: Supplied in USP grade purified water
40nm Carboxylated (carboxyl-PEG3000-SH) Silver Nanoparticles
RN-CY- SC3K-40-25
Silver nanoparticle core size: 40nm (+/- 3nm)
Size dispersity: CV <18%
Surface composition: carboxyl-PEG3000-SH/methoxy-PEG2000-SH
Carboxyl surface density: 1/nm2
Absorption max: 410-425nm
Concentration: 1mg/ml
Optical Density (OD): 125
Particles per ml: ~2.8E+12
Formulation: Supplied in USP grade purified water
30nm Carboxylated (carboxyl-PEG5000-SH) Silver Nanoparticles
RN-CY-SC5K-30-25
Silver nanoparticle core size: 30nm (+/- 3nm)
Size dispersity: CV <18%
Surface composition: carboxyl-PEG5000-SH/methoxy-PEG2000-SH
Carboxyl surface density: 1/nm2
Absorption max: 400-410nm
Concentration: 1mg/ml
Optical Density (OD): 125
Particles per ml: ~7.0E+12
Formulation: Supplied in USP grade purified water
30nm Carboxylated (carboxyl-PEG3000-SH) Silver Nanoparticles
RN-CY-SC3K-30-25
Silver nanoparticle core size: 30nm (+/- 3nm)
Size dispersity: CV <18%
Surface composition: carboxyl-PEG3000-SH/methoxy-PEG2000-SH
Carboxyl surface density: 1/nm2
Absorption max: 400-410nm
Concentration: 1mg/ml
Optical Density (OD): 125
Particles per ml: ~7.0E+12
Formulation: Supplied in USP grade purified water
20nm Carboxylated (carboxyl-PEG5000-SH) Silver Nanoparticles
RN-CY-SC5K-20-25
Silver nanoparticle core size: 20nm (+/- 3nm)
Size dispersity: CV <18%
Surface composition: carboxyl-PEG5000-SH/methoxy-PEG2000-SH
Carboxyl surface density: 1/nm2
Absorption max: 398-410nm
Concentration: 1mg/ml
Optical Density (OD): 125
Particles per ml: ~2.3E+13
Formulation: Supplied in USP grade purified water
20nm Carboxylated (carboxyl-PEG3000-SH) Silver Nanoparticles
RN-CY-SC3K-20-25
Silver nanoparticle core size: 20nm (+/- 3nm)
Size dispersity: CV <18%
Surface composition: carboxyl-PEG3000-SH/methoxy-PEG2000-SH
Carboxyl surface density: 1/nm2
Absorption max: 398-410nm
Concentration: 1mg/ml
Optical Density (OD): 125
Particles per ml: ~2.3E+13
Formulation: Supplied in USP grade purified water
10nm Carboxylated (carboxyl-PEG5000-SH) Silver Nanoparticles
RN-CY-SC5K-10-25
Silver nanoparticle core size: 10nm (+/- 3nm)
Size dispersity: CV <18%
Surface composition: carboxyl-PEG5000-SH/methoxy-PEG2000-SH
Carboxyl surface density: 1/nm2
Absorption max: 390-405nm
Concentration: 1mg/ml
Optical Density (OD): 125
Particles per ml: ~1.8E+14
Formulation: Supplied in USP grade purified water
10nm Carboxylated (carboxyl-PEG3000-SH) Silver Nanoparticles
RN-CY-SC3K-10-25
Silver nanoparticle core size: 10nm (+/- 3nm)
Size dispersity: CV <18%
Surface composition: carboxyl-PEG3000-SH/methoxy-PEG2000-SH
Carboxyl surface density: 1/nm2
Absorption max: 390-405nm
Concentration: 1mg/ml
Optical Density (OD): 125
Particles per ml: ~1.8E+14
Formulation: Supplied in USP grade purified water
Properties
The carboxyl functionalized silver nanoparticle surface allows for covalent conjugation of antibodies, proteins and other ligands using standard EDC/NHS coupling chemistry.
The precisely engineered silver nanoparticle surface with extended carboxyl groups maximizes conjugation efficiency by minimizing steric hindrance while still maintaining low non-specific protein binding. These features results in reliable and reproducible conjugates.
Storage
Store product away from light at 4°C. Do NOT freeze.
When stored as specified the product is stable for at least three months.
