Product Overview
PEG-NHS Ester Disulfide Chemical Structure: Polyethylene glycol (PEG) modified with an N-hydroxysuccinimide (NHS) ester and a disulfide bond. Bi-functional molecule facilitating cross-linking and conjugation with thiol groups in biological molecules. Highly soluble in water and organic solvents, enabling versatile applications.
Key factor
- PEG NHS Ester Disulfide Structure: Consists of a polyethylene glycol (PEG) backbone with NHS ester and disulfide functional groups.
- High Reactivity: The NHS ester enables efficient conjugation with amine groups on proteins, peptides, and other biomolecules.
- Cleavable Linker: The disulfide bond allows for controlled cleavage under reducing conditions, making it useful for reversible modifications.
- Solubility: PEG increases the solubility of hydrophobic molecules in aqueous solutions.
- Biocompatibility: PEG is non-toxic and biocompatible, making it suitable for use in biological systems.
Applications
- Bioconjugation: Ideal for linking proteins, peptides, and antibodies to various surfaces or other biomolecules.
- Drug Delivery: Used in the design of drug delivery systems where controlled release is required.
- Surface Modification: Functionalizes surfaces of nanoparticles, beads, and other materials for biomedical applications.
- Protein Immobilization: Enables the stable immobilization of proteins on biosensors and diagnostic devices.
- Controlled Release Systems: Applied in creating systems where the drug or biomolecule release can be controlled through disulfide cleavage.
Advantages
- Efficiency: High conjugation efficiency due to the reactive NHS ester group.
- Versatility: Suitable for a wide range of applications in biochemistry and nanotechnology.
- Controlled Release: The disulfide bond allows for controlled and reversible modification.
- Enhanced Solubility: PEG improves the solubility of hydrophobic drugs and biomolecules.
- Stability: Provides stability to the conjugated biomolecules, extending their functional life.
Why HIYKA
Hiyka ensures high purity and consistent quality of PEG NHS Ester Disulfide products. With a team of experienced researchers and advanced manufacturing facilities, Hiyka offers products that meet stringent research and industrial standards. Provides excellent customer service and technical support to help researchers achieve their goals. Hiyka is committed to continuous innovation, offering cutting-edge products that support advanced research and development. Offers a wide range of related products and solutions, making it a one-stop shop for researchers in biotechnology and nanotechnology.
