Product Overview
Biotin-PEG-Disulfide is a versatile reagent used in bioconjugation and surface modification applications. This compound features a biotin moiety linked to a polyethylene glycol (PEG) chain with a disulfide bond. The biotin group provides a strong and specific binding affinity to streptavidin and avidin proteins, while the PEG chain enhances solubility and reduces non-specific binding. The disulfide bond enables reversible attachment, making it ideal for various dynamic biological and chemical processes.
Key factor
- High Affinity Binding: Biotin provides a strong, specific interaction with streptavidin/avidin.
- Enhanced Solubility: The PEG chain improves solubility in aqueous solutions.
- Reduced Non-specific Binding: PEG minimizes non-specific interactions with biological molecules.
- Reversible Attachment: The disulfide bond allows for reversible conjugation, useful in dynamic studies.
- Biocompatibility: PEG is known for its biocompatible properties, making it suitable for in vivo applications.
Applications
- Bioconjugation: Attaching biomolecules such as proteins, peptides, and antibodies for research and diagnostic purposes.
- Surface Modification: Coating surfaces like nanoparticles, sensors, and microplates to reduce non-specific binding and improve biocompatibility.
- Drug Delivery: Conjugation to therapeutic molecules for targeted drug delivery systems.
- Diagnostics: Used in assays and imaging techniques for the detection and quantification of various analytes.
- Biosensors: Enhancing the performance of biosensors by providing a stable and biocompatible interface.
Advantages
- Versatility: Suitable for a wide range of bioconjugation and surface modification applications.
- Specificity: Strong and specific interaction with streptavidin/avidin ensures reliable conjugation.
- Reversible: Disulfide bond allows for controlled attachment and release.
- Enhanced Performance: PEG chain improves solubility and reduces non-specific interactions, enhancing overall performance in biological environments.
- Biocompatible: Safe for use in biological systems, including in vivo applications.
Why HIYKA
Hiyka offers rigorously tested, high-purity Biotin-PEG-Disulfide to ensure consistent and reliable results. With extensive experience in nanomaterials and bioconjugation, Hiyka provides products designed to meet the specific needs of advanced research and industrial applications. Hiyka offers excellent customer service and technical support to assist with product selection and application guidance. Committed to continuous innovation, Hiyka stays at the forefront of nanotechnology and bioconjugation advancements, ensuring access to the latest and most effective materials. Hiyka serves a global customer base, providing fast and reliable delivery worldwide.
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