Alkyne functionalized gold nanoparticles are precisely engineered for covalent conjugation to any molecule tagged with an azide group.
With the use of a copper(I) catalyst, the alkyne group on the gold and the azide-tagged molecule undergo a cycloaddition to form a stable and permanent linkage. The reaction between these 2 functional groups typically occurs rapidly, in high yield, and with no by-products, meaning that the customer will always have a stable conjugate and enough of it to use in subsequent downstream applications such as lateral flow assays and imaging.
These reactions are also especially useful in applications involving oligonucleotides due to the higher prevalence of azide modifications.
Alkyne functionalized gold nanoparticles are available in 12 different sizes ranging from 5nm – 100nm,
& are more than 95% spherical and have a uniform size distribution (CV <12%). Products are provided as suspensions at 50 OD.
- Composition: Alkyne gold nanoparticles
- Core Size: 5nm,10nm,30nm....100nm.
- Absorption max: 515-520nm
- Optical Density (OD): 50
- Particles per ml: 2.73E+15
- Alkyne Surface Density: ~1/nm2
- Formulation: Supplied in USP grade purified water
Properties
- Alkyne functionalized gold nanoparticles are suitable for covalent conjugation of any molecule with an azide through click chemistry.
- These gold nanoparticles allow for rapid generation of gold conjugates and unique gold nanoparticle surface chemistries.
- Our Alkyne functionalized gold nanoparticles are available in 12 different sizes ranging from 5 -100nm, are more than 95% spherical and have uniform size distribution (CV <12%).
- All of our batches go through stringent quality control prior to shipment to our customers using dynamic light scattering to guarantee size and monodispersity and lot specifications are supplied with each product.
Storage
Store product away from direct sunlight at 4°C. Do NOT freeze. When stored as specified the product is stable for at least twelve months.