mPEG-16 Thiol

PEG oligomers are processed into a variety of derivatives. A high purity for intermediates and products is maintained, and our catalogue items have an overall purity exceeding 95%. In comparison to PEG products obtained from polydisperse material, the use of our compounds is therefore more consistent.

Available: 1g, 5g

SKU: RN-PL-PEG16-T Category:

Product Overview

MPEG-16-Thiol represents a sophisticated chemical tool designed for a broad range of applications in bioconjugation, drug delivery systems, and material science. By combining the hydrophilic and biocompatible properties of methoxy polyethylene glycol (MPEG) with the reactive functionality of a thiol group, MPEG-16-Thiol offers unique advantages for creating stable and effective conjugates, enhancing solubility, and enabling targeted delivery mechanisms.

Key factor

  • Reactive Thiol Group: Offers a highly reactive site for conjugation with maleimide, halogen, and metal surface groups, enabling a broad range of bioconjugation and material modification applications.
  • Hydrophilicity: The MPEG backbone ensures water solubility, improving the solubility of conjugated molecules or particles in biological and aqueous environments.
  • Biocompatibility: Exhibits low toxicity and minimal immunogenicity, making it suitable for biomedical and pharmaceutical applications.
  • Versatility: Can be used to modify a wide variety of substrates, including proteins, peptides, drugs, nanoparticles, and surfaces, providing tailored functionality.

Applications

  • Drug Delivery Systems: Used in the development of PEGylated drugs and nanoparticles for targeted drug delivery, reducing immunogenicity and improving circulation time.
  • Protein and Peptide Conjugation: Enables the conjugation of therapeutic proteins and peptides, enhancing their stability and therapeutic efficacy.
  • Surface Engineering: Applied in modifying the surfaces of materials, including nanoparticles and medical devices, to improve biocompatibility and functionality.
  • Biosensors and Diagnostics: Utilized in the construction of biosensors and diagnostic tools, providing specific and stable attachment of biomolecules.

Advantages

  • Enhanced Bioconjugation: Facilitates the efficient and stable attachment of therapeutic molecules to carriers or active sites, optimizing therapeutic delivery.
  • Improved Drug Solubility and Stability: Increases the solubility and stability of hydrophobic drugs in aqueous environments, enhancing bioavailability and therapeutic effect.
  • Surface Modification: Allows for the precise modification of material surfaces, imparting desired properties such as biocompatibility and targeted binding capabilities.
  • Customization and Flexibility: Supports the development of custom-tailored materials and therapeutics, meeting specific research and clinical needs.

Why HIYKA

MPEG-16-Thiol is a versatile and powerful compound that bridges the gap between chemical functionality and biological application. Its ability to improve solubility, biocompatibility, and reactive conjugation makes it an essential component in the toolkit of researchers and developers across biochemistry, pharmaceuticals, and materials science. The potential applications of MPEG-16-Thiol continue to expand, driving innovation and enabling new solutions in health care and material design.

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