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Human CRP ELISA Kit
RN-CY-EL-009
C-reactive protein (CRP) is a 115 kDa polypeptide belonging to the pentraxin family, consisting of noncovalently linked 23 kDa subunits forming a homopentameric structure. This acute-phase inflammatory protein is secreted by hepatic cells and plays a vital role in linking innate and adaptive immunity. It achieves this by activating the classical complement pathway and interacting with immune cells via Fcγ receptor binding.
ELISA, ELISA kit
Product Overview
C-reactive protein (CRP) is a 115 kDa polypeptide belonging to the pentraxin family, consisting of noncovalently linked 23 kDa subunits forming a homopentameric structure. This acute-phase inflammatory protein is secreted by hepatic cells and plays a vital role in linking innate and adaptive immunity. It achieves this by activating the classical complement pathway and interacting with immune cells via Fcγ receptor binding.
In healthy adults, CRP levels are typically below 3 µg/mL. During inflammatory conditions, CRP levels can increase significantly, rising from approximately 1 µg/mL to over 500 µg/mL within 24–72 hours following severe tissue damage such as trauma or progressive cancer. Emerging research suggests that CRP levels may also serve as an indicator for individuals at higher risk of heart attacks.
CRP is a crucial biomarker and mediator in inflammation and immune response, making it essential for diagnostic and research purposes. It aids in the study of conditions such as bacterial infections, autoimmune diseases, and chronic inflammatory disorders.
Key Benefits:
- Ease of Use: Ready-to-use kit; simply add standards and samples to wells without blocking or rehydration steps.
- High Performance: Offers excellent sensitivity, specificity, and reproducibility.
- Validated Applications: Fully validated for use in the listed sample types.
- Flexible Plate Design: Includes a 96-well plate, breakable into 12 x 8 well strips for efficient assay setup.
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Product Specification
| Protein name | C Reactive Protein |
| Alternate names |
C Reactive Protein; C-reactive protein(1-205); C-reactive protein, pentraxin-related; CRP; pentraxin 1; PTX1 |
| Species reactivity | Human |
| Assay format | Solid-phase Sandwich ELISA (quantitative) |
| Sample type | Serum, Plasma, Cell culture supernatant |
| Sample volume | 100 μL |
| Assay length | 4.5 hrs |
| Analytical sensitivity | <10 pg/mL |
| Assay range | 31.2 – 2000 pg/ml |
| Intra-assay CV | <5% |
| Inter-assay CV | <6.5% |
| Recovery (%) | Serum: 98.9 Plasma: 90.7 Cell culture media: 93.1 |
| Detection & Instrument | Colorimetric, Microplate Reader |
| UniProt ID | (Human) P02741 |
Product Sheet – Human CRP ELISA Kit
Handbook – Human CRP ELISA Kit
Safety Data Sheet (SDS) – Human CRP ELISA Kit
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