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Human CXCL10 ELISA Kit
RN-CY-EL-008
CXCL10, also known as interferon-inducible protein 10 (IP-10), is a 10 kDa Th1-chemokine belonging to the CXC family. This molecule exhibits diverse functions by interacting with the CXC receptor 3 (CXCR3). It plays a pivotal role in recruiting various immune cells, including Th1 cells, dendritic cells, NK cells, γδ T cells, and macrophages. CXCL10 is primarily produced by neutrophils, leukocytes, monocytes, eosinophils, and non-immune cells such as stromal cells, keratinocytes, epithelial cells, and endothelial cells.
ELISA, ELISA kit
Product Overview
CXCL10, also known as interferon-inducible protein 10 (IP-10), is a 10 kDa Th1-chemokine belonging to the CXC family. This molecule exhibits diverse functions by interacting with the CXC receptor 3 (CXCR3). It plays a pivotal role in recruiting various immune cells, including Th1 cells, dendritic cells, NK cells, γδ T cells, and macrophages. CXCL10 is primarily produced by neutrophils, leukocytes, monocytes, eosinophils, and non-immune cells such as stromal cells, keratinocytes, epithelial cells, and endothelial cells.
In healthy individuals, CXCL10 levels typically range from 24 pg/mL to 933 pg/mL. Elevated CXCL10 levels are associated with several human diseases, including infectious diseases, inflammatory and autoimmune disorders, and cancer. It exacerbates inflammation and induces tissue damage by guiding leukocytes to affected tissues.
CXCL10 is highly significant in biomedical research, both diagnostically and therapeutically. Monitoring CXCL10 levels helps in diagnosing and tracking disease progression. Additionally, targeting its activity or blocking its interaction with CXCR3 is a potential strategy for developing innovative treatments for immune-related disorders and cancer.
ELISA Kit Benefits
- Ease of Use: Ready-to-use format; simply add standards and samples to the wells without the need for time-consuming blocking or rehydration steps.
- Superior Performance: Offers high sensitivity, specificity, and reproducibility.
- Comprehensive Validation: Fully validated for a wide range of sample types.
- Flexible Design: 96-well plate breakable into 12 x 8 well strips for customizable use.
This product is ideal for researchers in India seeking reliable tools for immune-related studies and diagnostics.
Download: ELISA Product Brochure
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Product Specification
| Protein name | C-X-C motif chemokine ligand 10 (CXCL10) |
| Alternate names |
Interferon gamma-induced protein 10, IP-10, Gamma-IP10, small-inducible cytokine B10, gIP-10 |
| Species reactivity | Human |
| Assay format | Solid-phase Sandwich ELISA (quantitative) |
| Sample type | Serum, Plasma, Cell culture supernatant |
| Sample volume | 100 μL |
| Assay length | 4.5 hrs |
| Analytical sensitivity | <8 pg/mL |
| Assay range | 15.6 – 1000 pg/ml |
| Intra-assay CV | <5% |
| Inter-assay CV | <10% |
| Recovery (%) | Serum: 97.5 Plasma: 100.9 Cell culture media: 96.9 |
| Detection & Instrument | Colorimetric, Microplate Reader |
| UniProt ID | (Human) P02778 |
Product Sheet – Human CXCL10 ELISA Kit
Handbook – Human CXCL10 ELISA Kit
Safety Data Sheet (SDS) – Human CXCL10 ELISA Kit
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