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Gold Conjugation Kits for Thiolated Oligonucleotides

Unique OligoREADY™ gold conjugation kits have been optimized for high efficiency one-step conjugation of thiolated oligonucleotides directly to the gold surface of particles with diameters up to 100nm.

The kit contains ready-to-use pre-made mixtures. No activation, manipulation, or time consuming “salt-aging” steps are require for conjugation. Simply mix your reduced thiol-modified oligonucleotide with the pre-activated gold nanoparticles supplied with the kit. Conjugation of the oligonucleotide is achieved by the formation of a strong and stable gold-thiol bond without any additional linkers.

Features & Benefits

  • Allows conjugation of oligonucleotides to gold nanoparticles with sizes between 5nm-100nm.
  • Fast and convenient one-step conjugation reaction with no pre-activation requirements or manipulation of the gold nanoparticles.
  • Does not require time-consuming “salt-aging” procedures.
  • Results in a thiol-oligo conjugated directly to the gold surface without any linkers.

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Working with aptamers? Check out our AptamerREADY™ gold nanoparticles kits for easy and improved conjugation!

 

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