Carboxyl Silver Nanoparticles
Carboxyl functionalized silver nanoparticles are ideal for conjugation of proteins and other primary amine containing ligands using standard EDC/NHS coupling chemistry.
Our carboxylated silver nanoparticles are available in 8 different sizes ranging from 10-100nm, are more than 95% spherical and have uniform size distribution (CV <18%). In addition, the choice of two different length PEG surface spacer allows control of the distance between a conjugated molecule and the silver surface.
Features
- Superior size distribution compared to the leading competitor; available from 10nm to 100nm.
- Precisely engineered surface with an optimized carboxyl group density for easy conjugation.
Applications
- Ideal for development of silver conjugates for use in for example:
- Immunoblotting
- Lateral Flow Assays
- LSPR Assays
- Microscopy Applications (e.g. TEM, Darkfield)
100nm Carboxylated (carboxyl-PEG5000-SH) Silver Nanoparticles
RN-CY-SC5K-100-25
Silver nanoparticle core size: 10,20,30,40,50,60,80,100nm (+/- 3nm)
Size dispersity:Â CV <15%
Surface composition:Â carboxyl-PEG5000-SH/methoxy-PEG2000-SH
Carboxyl surface density:Â 1/nm2
Concentration:Â 1mg/ml
Formulation:Â Supplied in USP grade purified water
100nm Carboxylated (carboxyl-PEG3000-SH) Silver Nanoparticles
RN-CY-SC3K-100-25
Silver nanoparticle core size:Â 100nm (+/- 3nm)
Size dispersity:Â CV <15%
Surface composition:Â carboxyl-PEG3000-SH/methoxy-PEG2000-SH
Carboxyl surface density:Â 1/nm2
Absorption max:Â 480-520nm
Concentration:Â 1mg/ml
Optical Density (OD):Â 46
Particles per ml:Â ~1.8E+11
Formulation:Â Supplied in USP grade purified water
80nm Carboxylated (carboxyl-PEG5000-SH) Silver Nanoparticles
RN-CY-SC5K-80-25
Silver nanoparticle core size:Â 80nm (+/- 3nm)
Size dispersity:Â CV <15%
Surface composition:Â carboxyl-PEG5000-SH/methoxy-PEG2000-SH
Carboxyl surface density:Â 1/nm2
Absorption max:Â 445-465nm
Concentration:Â 1mg/ml
Optical Density (OD):Â 80
Particles per ml:Â ~3.5E+11
Formulation:Â Supplied in USP grade purified water
80nm Carboxylated (carboxyl-PEG3000-SH) Silver Nanoparticles
RN-CY-SC3K-80-25
Silver nanoparticle core size:Â 80nm (+/- 3nm)
Size dispersity:Â CV <15%
Surface composition:Â carboxyl-PEG3000-SH/methoxy-PEG2000-SH
Carboxyl surface density:Â 1/nm2
Absorption max:Â 445-465nm
Concentration:Â 1mg/ml
Optical Density (OD):Â 80
Particles per ml:Â ~3.5E+11
Formulation:Â Supplied in USP grade purified water
60nm Carboxylated (carboxyl-PEG5000-SH) Silver Nanoparticles
RN-CY-SC5K-60-25
Silver nanoparticle core size:Â 60nm (+/- 3nm)
Size dispersity:Â CV <15%
Surface composition:Â carboxyl-PEG5000-SH/methoxy-PEG2000-SH
Carboxyl surface density:Â 1/nm2
Absorption max:Â 425-440nm
Concentration:Â 1mg/ml
Optical Density (OD):Â 100
Particles per ml:Â ~8.5E+11
Formulation:Â Supplied in USP grade purified water
60nm Carboxylated (carboxyl-PEG3000-SH) Silver Nanoparticles
RN-CY-SC3K-60-25
Silver nanoparticle core size:Â 60nm (+/- 3nm)
Size dispersity:Â CV <15%
Surface composition:Â carboxyl-PEG3000-SH/methoxy-PEG2000-SH
Carboxyl surface density:Â 1/nm2
Absorption max:Â 425-440nm
Concentration:Â 1mg/ml
Optical Density (OD):Â 100
Particles per ml:Â ~8.5E+11
Formulation:Â Supplied in USP grade purified water
50nm Carboxylated (carboxyl-PEG5000-SH) Silver Nanoparticles
RN-CY-SC5K-50-25
Silver nanoparticle core size:Â 50nm (+/- 3nm)
Size dispersity:Â CV <18%
Surface composition:Â carboxyl-PEG5000-SH/methoxy-PEG2000-SH
Carboxyl surface density:Â 1/nm2
Absorption max:Â 415-430nm
Concentration:Â 1mg/ml
Optical Density (OD):Â 125
Particles per ml:Â ~1.4E+12
Formulation:Â Supplied in USP grade purified water
50nm Carboxylated (carboxyl-PEG3000-SH) Silver Nanoparticles
RN-CY-SC3K-50-25
Silver nanoparticle core size:Â 50nm (+/- 3nm)
Size dispersity:Â CV <18%
Surface composition:Â carboxyl-PEG3000-SH/methoxy-PEG2000-SH
Carboxyl surface density:Â 1/nm2
Absorption max:Â 415-430nm
Concentration:Â 1mg/ml
Optical Density (OD):Â 125
Particles per ml:Â ~1.4E+12
Formulation:Â Supplied in USP grade purified water
40nm Carboxylated (carboxyl-PEG5000-SH) Silver Nanoparticles
RN-CY-SC5K-40-25
Silver nanoparticle core size:Â 40nm (+/- 3nm)
Size dispersity:Â CV <18%
Surface composition:Â carboxyl-PEG5000-SH/methoxy-PEG2000-SH
Carboxyl surface density:Â 1/nm2
Absorption max:Â 410-425nm
Concentration:Â 1mg/ml
Optical Density (OD):Â 125
Particles per ml:Â ~2.8E+12
Formulation:Â Supplied in USP grade purified water
40nm Carboxylated (carboxyl-PEG3000-SH) Silver Nanoparticles
RN-CY-Â SC3K-40-25
Silver nanoparticle core size:Â 40nm (+/- 3nm)
Size dispersity:Â CV <18%
Surface composition:Â carboxyl-PEG3000-SH/methoxy-PEG2000-SH
Carboxyl surface density:Â 1/nm2
Absorption max:Â 410-425nm
Concentration:Â 1mg/ml
Optical Density (OD):Â 125
Particles per ml:Â ~2.8E+12
Formulation:Â Supplied in USP grade purified water
30nm Carboxylated (carboxyl-PEG5000-SH) Silver Nanoparticles
RN-CY-SC5K-30-25
Silver nanoparticle core size:Â 30nm (+/- 3nm)
Size dispersity:Â CV <18%
Surface composition:Â carboxyl-PEG5000-SH/methoxy-PEG2000-SH
Carboxyl surface density:Â 1/nm2
Absorption max:Â 400-410nm
Concentration:Â 1mg/ml
Optical Density (OD):Â 125
Particles per ml:Â ~7.0E+12
Formulation:Â Supplied in USP grade purified water
30nm Carboxylated (carboxyl-PEG3000-SH) Silver Nanoparticles
RN-CY-SC3K-30-25
Silver nanoparticle core size:Â 30nm (+/- 3nm)
Size dispersity:Â CV <18%
Surface composition:Â carboxyl-PEG3000-SH/methoxy-PEG2000-SH
Carboxyl surface density:Â 1/nm2
Absorption max:Â 400-410nm
Concentration:Â 1mg/ml
Optical Density (OD):Â 125
Particles per ml:Â ~7.0E+12
Formulation:Â Supplied in USP grade purified water
20nm Carboxylated (carboxyl-PEG5000-SH) Silver Nanoparticles
RN-CY-SC5K-20-25
Silver nanoparticle core size:Â 20nm (+/- 3nm)
Size dispersity:Â CV <18%
Surface composition:Â carboxyl-PEG5000-SH/methoxy-PEG2000-SH
Carboxyl surface density:Â 1/nm2
Absorption max:Â 398-410nm
Concentration:Â 1mg/ml
Optical Density (OD):Â 125
Particles per ml:Â ~2.3E+13
Formulation:Â Supplied in USP grade purified water
20nm Carboxylated (carboxyl-PEG3000-SH) Silver Nanoparticles
RN-CY-SC3K-20-25
Silver nanoparticle core size:Â 20nm (+/- 3nm)
Size dispersity:Â CV <18%
Surface composition:Â carboxyl-PEG3000-SH/methoxy-PEG2000-SH
Carboxyl surface density:Â 1/nm2
Absorption max:Â 398-410nm
Concentration:Â 1mg/ml
Optical Density (OD):Â 125
Particles per ml:Â ~2.3E+13
Formulation:Â Supplied in USP grade purified water
10nm Carboxylated (carboxyl-PEG5000-SH) Silver Nanoparticles
RN-CY-SC5K-10-25
Silver nanoparticle core size:Â 10nm (+/- 3nm)
Size dispersity:Â CV <18%
Surface composition:Â carboxyl-PEG5000-SH/methoxy-PEG2000-SH
Carboxyl surface density:Â 1/nm2
Absorption max:Â 390-405nm
Concentration:Â 1mg/ml
Optical Density (OD):Â 125
Particles per ml:Â ~1.8E+14
Formulation:Â Supplied in USP grade purified water
10nm Carboxylated (carboxyl-PEG3000-SH) Silver Nanoparticles
RN-CY-SC3K-10-25
Silver nanoparticle core size:Â 10nm (+/- 3nm)
Size dispersity:Â CV <18%
Surface composition:Â carboxyl-PEG3000-SH/methoxy-PEG2000-SH
Carboxyl surface density:Â 1/nm2
Absorption max:Â 390-405nm
Concentration:Â 1mg/ml
Optical Density (OD):Â 125
Particles per ml:Â ~1.8E+14
Formulation:Â Supplied in USP grade purified water
Properties
The carboxyl functionalized silver nanoparticle surface allows for covalent conjugation of antibodies, proteins and other ligands using standard EDC/NHS coupling chemistry.
The precisely engineered silver nanoparticle surface with extended carboxyl groups maximizes conjugation efficiency by minimizing steric hindrance while still maintaining low non-specific protein binding. These features results in reliable and reproducible conjugates.
Storage
Store product away from light at 4°C. Do NOT freeze.
When stored as specified the product is stable for at least three months.
